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Pomegranates: the fruity panacea

BBC News - November 28th, 2004

Scientists in Israel have shown that drinking a daily glass of the fruit's juice can reduce the risk of cardiovascular disease. "Pomegranate juice contains the highest antioxidant capacity compared to other juices, red wine and green tea," said Professor Michael Aviram, who led the team.

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Pomegranate Juice For Moms May Help Babies Resist Brain Injury

Science Daily - June 28th, 2005

Science Daily — St. Louis, June 28, 2005 -- Expectant mothers at risk of premature birth may want to consider drinking pomegranate juice to help their babies resist brain injuries from low oxygen and reduced blood flow, a new mouse study from Washington University School of Medicine in St. Louis suggests.

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Pomegranates and Prostate Cancer

Time Online Edition - September 27th,2005 -

Pomegranate juice appears to be the flavor of the month in health-food stores, supermarkets, and even in Sam's Club. But it may be a lot more than simply a refreshing and exotic taste: New research out of the University of Wisconsin Medical School suggests that it may help men stave off prostate cancer.

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Pomegranate juice decreases amyloid load and improves behavior in a mouse model of Alzheimer's disease

NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION - December 24th, 2006

Although there are no proven ways to delay onset or slow progression of Alzheimer's disease (AD), studies suggest that diet can affect risk. Pomegranates contain very high levels of antioxidant polyphenolic substances as compared to other fruits and vegetables. Polyphenols have been shown to be neuroprotective in different model systems.

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Antioxidant Power

LE MAGAZINE March 2000 - March, 2000

When it comes to antioxidant power, according to a measure called ORAC (oxygen radical absorbance capacity), blueberries are at the top of the USDA chart-ahead of blackberries, garlic, kale and strawberries, and far ahead of broccoli and spinach.

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Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer

NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION - February, 2002

Fresh organically grown pomegranates (Punica granatum L.) of the Wonderful cultivar were processed into three components: fermented juice, aqueous pericarp extract and cold-pressed or supercritical CO2-extracted seed oil. Exposure to additional solvents yielded polyphenol-rich fractions ('polyphenols') from each of the three components. Their actions, and of the crude whole oil and crude fermented and unfermented juice concentrate, were assessed in vitro for possible chemopreventive or adjuvant therapeutic potential in human breast cancer.

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Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E-deficient mice

NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION - May, 2002

BACKGROUND: Dietary supplementation with nutrients rich in antioxidants is associated with inhibition of atherogenic modifications to LDL, macrophage foam cell formation, and atherosclerosis. Pomegranates are a source of polyphenols and other antioxidants.

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Pomegranate juice may help to slow down the progress of prostate cancer, research suggests

BBC News - September 28th, 2005

Pomegranate juice may help to slow down the progress of prostate cancer, research suggests. Tests on mice showed the juice dramatically slowed down prostate cancer cell growth. Pomegranates, native to the Middle East, are packed with healthy anti-oxidants and anti-inflammatory agents. The study, by the University of Wisconsin, appears in Proceedings of the National Academy of Sciences. Prostate cancer is now the most common cancer diagnosed in men in the UK.

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Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation

NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION - June 24th, 2004

Dietary supplementation with polyphenolic antioxidants to animals was shown to be associated with inhibition of LDL oxidation and macrophage foam cell formation, and attenuation of atherosclerosis development. We investigated the effects of pomegranate juice (PJ, which contains potent tannins and anthocyanins) consumption by atherosclerotic patients with carotid artery stenosis (CAS) on the progression of carotid lesions and changes in oxidative stress and blood pressure. Ten patients were supplemented with PJ for 1 year and five of them continued for up to 3 years.

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Total antioxidant content of fruits

AMERICAN SOCIETY FOR NUTRITIONAL SCIENCES - June 23rd, 2004

Dietary supplementation with polyphenolic antioxidants to animals was shown to be associated with inhibition of LDL oxidation and macrophage foam cell formation, and attenuation of atherosclerosis development. We investigated the effects of pomegranate juice (PJ, which contains potent tannins and anthocyanins) consumption by atherosclerotic patients with carotid artery stenosis (CAS) on the progression of carotid lesions and changes in oxidative stress and blood pressure. Ten patients were supplemented with PJ for 1 year and five of them continued for up to 3 years.

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Fruits Offer Powerful Protection from Skin Cancer

AMERICAN ASSOCIATION FOR CANCER RESEARCH - October, 2003

Pomegranate Fruit Extract is a Novel Agent for Cancer Chemoprevention: Studies in Mouse Skin (Abstract 1547) The search for novel anti-cancer therapies is ongoing, especially in the area of skin cancer, which is the most frequently diagnosed malignancy in the United States. According to researchers from the University of Wisconsin, one promising agent against skin cancer may have been found in the extract of the pomegranate fruit.

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